A chalazion is a firm, nontender lump that arises from obstruction of a meibomian gland. Tenderness, when present, occurs during lid swelling and cyst formation. Both hordeola and chalazia are associated with blepharitis, inflammation of the lid margins associated with plugging of the glandular ducts, and crusting around the lashes. Conditions such as seborrheic dermatitis of the eyelids, rosacea, or rarely eyelash infestation with lice can cause blepharitis and resultant blockage of the meibomian glands.
Hordeolum. Focal swelling and erythema at the lid margin are seen in this hordeolum.
Chalazion. This chalazion shows nodular focal swelling and erythema from meibomian cyst formation. Pain is present during swelling and cyst formation.
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